The ECHELON Trail: An Illegal Vision

The clinical trail of TRAIL.

The naturally occurring tumour necrosis factor related apoptosis-inducing ligand (TRAIL) induces apoptosis through two death receptors, death receptor 4 (DR4) and death receptor 5 (DR5), that are expressed on the cell membrane. Binding of the ligand to the death receptors leads to activation of the extrinsic apoptosis pathway. Chemotherapy on the other hand stimulates the intrinsic apoptosis pa...

Expression of TRAIL and TRAIL receptors in colon carcinoma: TRAIL-R1 is an independent prognostic parameter.

PURPOSE Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) selectively induces apoptosis in cancer cells and may be involved in protection from metastases. TRAIL receptor (TRAIL-R) 1 and TRAIL-R2, but not TRAIL-R3 and TRAIL-R4, mediate apoptosis. We examined the expression of TRAIL and its receptors in normal and neoplastic colon epithelium, and studied its correlation with prognos...

Echelon analysis

Echelon Form

In this work we present the formalization of an algorithm to compute the Echelon Form of a matrix. We have proved its existence over Bezout domains and we have made it executable over Euclidean domains, such as Z and K[x]. This allows us to compute determinants, inverses and characteristic polynomials of matrices. The work is based on the HOL-Multivariate Analysis library, and on both the Gauss...

An Exploration of the Illegal Art Market of Australia

This report represents a first exploration of the place of illegality in the art market of Australia. It draws upon qualitative data, including interviews and field observations involving over 300 respondents (dealers, museum personnel, police, insurance representatives, and other) to examine the general size and dimensions of theft and fraud in the art world. The report observes that both thef...